I’ve been a smoker for 45 years I’ve been on the pre lung cancer screening since 2018 at which time I had about 10 nodules that were suspicious. In 2019 one of them seemed to be growing quickly so rather than do a biopsy, because it was hard to get to, they did a segmentectomy and removed the top 1/8 to ¼ top of my left lower lobe to remove the entire nodule. Which after testing turned out to be: Histologic Type: Invasive adenocarcinoma, micropapillary predominant, other subtypes present include acinar (20%). Since then I’ve been getting a CT scan every six months and an occasional PET scan. I have two ground grass nodules that are of particular interest that are growing at a faster rate than the other ones which are mostly solid. Based on the testing of the one that was removed there’s about a 90% certainty that these are of the same genre. The growth rate is very slow they’ve only grown about 1 centimeter in all three dimensions in the last five years.
The purpose of this post and to start the discussion to find out if there are repurposed drugs that can hinder or stop the growth of these nodules. I have tried various things over the last five years but not intensely and none of it seemed to do make a difference the growth rate seems to be consistent, but slow. My most recent PET scan does show an uptake of glucose but at a very low level the lightest color on the PET scan that you can have.
All the things that I’ve read about repurposed drugs and the way they work on the pathways they really need an active pathway to do their job. Am I understanding this correctly? I guess my question is that since the activity at such a low level what kind of repurposed drug could work at that level and would I have to take it continuously in order to be always present in the body?
You might want to watch the IMA webinar from last night (11/5/25) on cancer. It was very informative and many resources available on the IMA website were mentioned.
After the webcast of last night, you need to hunt for an integrative oncologist, ideally through this site. Also get a copy of Paul Marik’s Cancer Care second Edition. Focus on the lifestyle tomorrow before you can research an integrative Oncologist…
Friend, sorry for your health news. Make sure you have plenty of spiritual and emotional support. Makes a world of difference in outlook over outcome.
You’re searching for a more precise approach and I’d point you and your integrative oncologist towards Astron Health (based in England). They can do genomic testing on your malignant tissue samples and determine a more particular recommendation for metabolic pathways to up or down regulate unique to you. No, you don’t need to travel there. And remember, if there’s no integrative oncologist nearby, you could consult IMA for telehealth referral options. Astron might also have additional names with whom they’re networked. Always worth asking. Finally, type “integrative oncology” into the search field of something like Apple Podcasts and find other integrative oncs who’ve been interview guests. The movement is growing! Many of those might be willing to do telehealth appointments.
Thank you for your question.. there is no simple answer.
From what you are describing this is a low grade tumor with low activation of the glycolytic pathways.
Nevertheless, the fact that it is malignant and the fact that the PET is positive (albeit at a low level) indicates that the cancer is driven by metabolic reprogramming and glycolytic enzyme activation.
Therefore, anti-Warburg repurposed drugs should slow the growth of the tumor.. see table below and attachment.
These should be taken for ever. i.e the rest of your life.
In addition, it is important to follow a low glycemic diet; ideally ketogenic.
Thanks. I actually did extensive genomic testing of my tumor back in 2022. (Genomics for Life in Australia.) I have no evidence of cancer for almost 4 years so my recurrence risk has definitely dropped but is still there.
