I have been thinking about the question of drug interactions, and how they can be used to create a negative adaptive landscape for cancer cells. I believe it’s possible to do some optimization for individual patients, without going too deep into the ‘personalized genomics’ space in cancer, which has greatly let down on its original aims.
I am working on a more academic article on using resources like Broad Institute’s DEPMAP to find repurposed drugs combination. Several other repurposed drugs databases for cancer.
We’ve also been trying to find out what types of dosing schedules are being used for items such as ivermectin, mebendazole, nitazoxanide, pyrantal pamoate etc. Does anyone have a recommended guide for any of the trials they’ve been putting together for these specific products? Much appreciation in advance.
Thank you @kmorros! Very helpful, will forward to some of our network of providers. Are there any groups looking to run or are running clinical trials on these treatment options that I could connect them with as well?
Yes, I was thinking in particular looking at current repurposed drugs database. DEPMAP from the Broad institute is a great ‘big data’ approach to looking at drugs and how they impact specific cancer cell lines. In my own academic work I’ve been looking at using their data to predict multidrug impacts on particular cell lines.
I think people in general are intelligent enough to know that the guide isn’t meant to be a kitchen sink approach, but to present options which one may consider in their treatment. There is some tailoring for individual cancer types, I think this can be done at a rough level without investing a great deal of time for each personalized cancer phenotype.
Good morning from South Florida USA Steve. My name is Dr. Tara Solomon. I am currently treating 6 stage 4 cancer patients, 2 with prostate, 2 with colon cancer , 1 breast and one ovarian cancer with Fendbendazole and Ivermectin . Most have stopped chemotherapy. Every one of them has responded with decreased tumor size and or tumor markers. My WhatsApp number is +1-561-425-8890. Please reach me there. There is a way to ship medications to you in Australia from my compounding pharmacy. It will save you money.
Sincerely,
Tara A. Solomon MD
Medical Director The Women’s Wellness Center of South Florida